Monica Di Fiore obtained a PhD in Analysis of Public Policies, University of Rome, La Sapienza.
Worked between 2005 and 2009 on innovation and competitiveness of the national industrial system (“Models and evaluation tools for evaluating the mid-term impact of investments in research and innovation” - project FIRB RBNEETJY).
Between 2007 and 2008, she worked on the European FP6 project “Create Acceptance” exploring and studying economic, political, and social barriers to the take up of renewable energies in local contexts.
She continued to work on social acceptance of technologies in the field of renewable energies and since 2013 of themes related to science communication, open science, and responsible research and innovation, publishing the volume “Scienziati in Affanno” , edited by CNR.
More recently, has worked on the reproducibility crisis, on science-based regulatory capture , and on issues linked to sociology and ethics of quantification , contributing to a manifesto published by Nature on the quality of Mathematical models .
At present, she is conducting an analysis of a possible observatory for the ethics of quantification concerned with visible and invisible numbers produced by statistics, mathematical models, and algorithms , and collaborating  with the Norwegian Economist Erik Reinert whose book  she is translating into Italian.
 A. L’Astorina and M. Di Fiore, Scienziati in affanno? Ricerca e Innovazione Responsabili (RRI) in teoria e nelle pratiche. Rome: CNR Edizioni, 2018.
 A. Saltelli, D. J. Dankel, M. Di Fiore, N. Holland, and M. Pigeon, “Science, the endless frontier of regulatory capture,” Futures, 135 (2022) 102860. https://doi.org/10.1016/j.futures.2021.102860.
 A. Saltelli and M. Di Fiore, “From sociology of quantification to ethics of quantification,” Humanit. Soc. Sci. Commun., vol. 7–69, 2020, [Online]. Available: https://www.nature.com/articles/s41599-020-00557-0.epdf
 A. Saltelli, G. Bammer, I. Bruno, E. Charters, M. Di Fiore, E. Didier, W. Nelson Espeland, J. Kay, S. Lo Piano, D. Mayo, R.J. Pielke, T. Portaluri, T.M. Porter, A. Puy, I. Rafols, J.R. Ravetz, E. Reinert, D. Sarewitz, P.B. Stark, A. Stirling, Jeroen P. van der Sluijs, P. Vineis, Five ways to ensure that models serve society: a manifesto, Nature 582 (2020) 482–484.
 M. Di Fiore, M. Kuc Czarnecka, S. Lo Piano, A. Puy, and A. Saltelli, “The Agency of quantification,” Minerva, vol. Sumbitted, 2022.
 E. S. Reinert, M. Di Fiore, A. Saltelli, and J. R. Ravetz, “Altered States: Cartesian and Ricardian dreams,” UCL Institute for Innovation and Public Purpose, London, IIPP WP 2021/07, 2021.
 E. S. Reinert, How rich countries got rich and why poor countries stay poor. Public Affairs, 2008.